Researchers have identified a potential treatment strategy for Rett syndrome via alternative splicing modulation of the MECP2 gene.
Alternative splicing (AS) is a genetic process that increases the diversity of proteins that can be generated from genes, by assembling sections of genetic code into different combinations. This is ...
Aging is a major risk factor for chronic diseases, and calorie restriction (CR) is a robust non-pharmacological intervention ...
Alternative splicing is a genetic process where different segments of genes are removed, and the remaining pieces are joined together during transcription to messenger RNA (mRNA). This mechanism ...
Aging is a major risk factor for chronic diseases, and calorie restriction (CR) is a robust non-pharmacological intervention that can extend health ...
Scientists at Università Cattolica reported on the discovery of a genetic mechanism that pancreatic cancer cells employ to evade treatment, and which the investigators say could pave the way to the ...
Alternative splicing promises to help resolve the question of how 25,000 genes could possibly be enough to encode instructions for a huge range of specialized human cells from osteoplast to neuron.
A therapeutic strategy based on alternative splicing of the MECP2 gene could restore protein levels in Rett syndrome, a neurological disorder caused by mutations in that gene. Scientists at Baylor ...
In an important new study, Chinese researchers have discovered the previously unrecognized role of alternative splicing of the DOC2A gene in schizophrenia. The research was conducted by scientists led ...
In eukaryotic genetics, the one-gene/one-protein concept has, for the most part, breathed its last. Researchers have rallied behind mechanisms such as alternative splicing, which may allow a lowly ...