ACLY is crucial for establishing and maintaining the pro-inflammatory SASP. The ACLY-BRD4 axis enhances the aging-related inflammatory response. Therefore, inhibiting the ACLY-BRD4 axis helps create ...
Researchers developed a biomimetic nanovesicle that crosses the blood-brain barrier, degrades DNA repair proteins, and restores temozolomide sensitivity in glioblastoma. (Nanowerk Spotlight) ...
BOSTON--(BUSINESS WIRE)--DeepCure, a therapeutics company using AI to discover novel drugs for inflammation and immune diseases, will present new in vivo data demonstrating its selective BRD4 (BD2) ...