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Taking images of tiny structures within cells is tricky business. One technique, cryogenic electron tomography (cryoET), ...

Fifty years ago, a group at the US National Bureau of Standards published the first protocol for embedding preserved tissue with plastic, and showed that such methacrylate-embedded specimens were ...

Researchers have combined two microscopic imaging techniques in one microscope, providing scientists with a high-resolution method of tracking single molecules in a cellular context. The development ...

The Electron Microscopy shared resource offers techniques that allow researchers to resolve structures from cellular ultrastructure all the way down to molecular interactions. Our expertise in EM ...

For more than 50 years, freeze-fracture electron microscopy has been widely accepted as a significant method in microscopic structural and biological research. Although components of the approach were ...

Jeremy Berg does not work for, consult, own shares in or receive funding from any company or organization that would benefit from this article, and has disclosed no relevant affiliations beyond their ...

SLAC researchers develop an approach to better guide the preparation of cell slices for cryogenic electron tomography imaging ...