This illustration shows the major cell types affected by cellular senescence in various skeletal diseases. As the body ages, senescent cells accumulate in different tissues—including bone, cartilage, ...

Improvements in public health have allowed humankind to survive to older ages than ever before, but, for many people, these added golden years are not spent in good health. Aging is a natural part of ...

Northwestern Medicine scientists have discovered how molecular "traffic controllers" in cells influence aging and cellular senescence—a state where cells stop dividing but remain metabolically active.

Researchers found that the body’s natural recycling system, the lysosome, plays a vital role in removing the protein that drives premature aging. When this system breaks down, aging speeds up. By ...

As we age, our cells don’t just wear down—they reorganize. Researchers found that cells actively remodel a key structure called the endoplasmic reticulum, reducing protein-producing regions while ...

Aging is a complex biological process characterized by the progressive decline of physiological integrity, leading to impaired function and increased vulnerability to disease. It is the strongest risk ...

Recent breakthroughs in anti-aging research have opened up exciting possibilities for extending human healthspan. Scientists worldwide are uncovering innovative treatments that target the underlying ...

Demonstrates how dual-purpose therapeutic targets may address both hepatocellular carcinoma progression and cellular senescence, supporting emerging strategies that link disease treatment with aging ...

Health experts tend to go back and forth on whether or not caffeine is actually good for you, or how much you should ingest every day. No matter which side you land on, there's no arguing that a cup ...

Researchers from the University of California San Diego Sanford Stem Cell Institute have discovered that spaceflight accelerates the aging of human hematopoietic stem and progenitor cells (HSPCs), ...