Every time our body encounters a new disease-causing agent, a crucial defense system called adaptive immunity comes into play ...

Drug discovery is shifting from static snapshots to moving pictures. Instead of inferring how medicines work from end results ...

A research team of the University Medical Center Mainz has succeeded in observing for the first time how G protein-coupled ...

Scientists are aiming to determine the composition and topology of physiological Ashwell-Morell receptor ligands. Their findings will help uncover the receptor's still-hidden secrets. After earning ...

Many people are familiar with histamine, a biological molecule that serves as a key driver of allergic reactions and other ...

Receptors are cellular components that trigger internal changes based on external signals. Researchers have built a new synthetic receptor with incredibly broad potential to program cell activity, ...

A new study shows how the single-molecule organization of receptors in a cellular context determines the function of antibodies, opening up new pathways for the development of cancer immunotherapies.

A bitter taste has always been considered a warning signal, devoted to protecting us from ingesting potentially harmful ...

New Cell-Based Assays Support Drug Discovery Across the Amylin Receptor Family STATE COLLEGE, PA, UNITED STATES, ...

The scientists demonstrated an absence of Ashwell-Morell receptor ligands on glycoforms of intestinal alkaline phosphatase (IAP) featuring glycan chains with two antennae, known as biantennary. They ...