HISTOCHEMICAL reactions are dependent on enzyme specificity. The reaction should be enhanced by conditions that are optimal for the enzyme and should be diminished in the presence of inhibitors.

Background: Perchlorate (ClO₄⁻) is an environmental contaminant known to disrupt the thyroid axis of many terrestrial and aquatic species. ClO₄⁻ competitively inhibits iodide uptake into the thyroid ...

Objective: To compare angiotensin-converting enzyme (ACE) inhibitor use in patients with type 2 diabetes at 1 year and 3 years after guidelines were published. Study Design: Retrospective database ...

The results of a preclinical study by lymphoma researchers at Weill Cornell Medicine suggest that an emerging class of anticancer drugs called EZH2 inhibitors may greatly enhance the potency of some ...