A new, epidemic strain of C. difficile is proving alarmingly deadly, and new research from the University of Virginia School of Medicine not only explains why but also suggests a way to stop it. Until ...

PhD student Carrie A. Cowardin was working in the lab of Bill Petri, MD, PhD, chief of the University of Virginia’s Division of Infectious Diseases and International Health in Charlottesville, when ...

The presence of antigen-specific and neutralizing antibodies was not associated with Clostridioides difficile infection symptoms, severity, therapy approach, treatment response, or recurrences in a ...

A new article details a research breakthrough that provides a promising starting point for scientists to create drugs that can cure C. diff -- a virulent health care-associated infection that causes ...

A study published by PNAS explains breakthrough research around designing drugs that target C. diff bacterial infections that result in 15,000 deaths in the U.S. annually. The bacterium is potentially ...

Hospital acquired infections are a serious public health concern. According to the Centers for Disease Control (CDC), the bacteria Clostridium difficile is estimated to have caused around half a ...

Loo VG, Poirier L, Miller MA, et al. A predominantly clonal multi-institutional outbreak of Clostridium difficile-associated diarrhea with high morbidity and mortality. N Engl J Med.

Future Microbiol. 2012;7(8):945-957. Patients infected with PCR ribotype 027 were found to have more severe diarrhea, higher mortality and more reoccurrences of symptoms. [44] It has been thought that ...

Clostridiodes difficile infection has become a leading cause of severe, sometimes fatal diarrheal illness, with the bacterium's toxins causing the damage. New work cements our knowledge of how C. diff ...

In a hamster model of Clostridium difficile, infection with C. difficile strains producing either toxin A or toxin B caused fulminant disease, according to a research team from the University of ...