A Purdue University team has discovered a new therapeutic target for triple-negative breast cancer. The research, led by Kyle ...

The team applied this method to mRNA/saRNA constructs from 1 to 10 kb and assessed pH ranges from 3 to 6. For all the RNA constructs, the J2 immunoblot signal—a marker for dsRNA strands—decreased with ...

A biochemistry assistant professor and graduate student have discovered a new therapeutic target for triple-negative breast cancer.

Purdue researchers identify the PACT protein as a potential target for triple-negative breast cancer, opening new paths for ...

Multiple forms of double-stranded RNA (blue, magenta, orange structures) cross cell membranes with the help of a conserved protein located in novel sites (colored by depth) throughout the roundworm's ...

There are many molecules with therapeutic potential, but it can be a challenge to deliver them to the right places at the right times. RNA is one such molecule; the sequences for different proteins ...

MYC‑driven tumors silence innate immune alarms by clearing R‑loop–derived signals, exposing a new therapeutic angle for targeting MYC without broad inhibition.

Scientists at IOCB Prague are uncovering new details of gene transcription. They have identified a previously unknown ...

RNA-based medicines are one of the most promising ways to fight human disease, as demonstrated by the recent successes of RNA vaccines and double-stranded RNA (dsRNA) therapies. But while health care ...