Biological cells invest much of their resources into the production of enzymes, which catalyze the conversion of substrates into products. An international team of bioinformaticians and biophysicists ...
Enzymes are the molecule factories in biological cells. However, which basic molecular building blocks they use to assemble target molecules is often unknown and difficult to measure. An international ...
Using artificial intelligence, researchers show how γ-secretase recognizes substrates - an important advance for fundamental and translational research. The γ-secretase enzyme is capable of cleaving ...
Halogenated compounds are widespread in the pharmaceutical and agrochemical industries. But the reagents used to make them can produce hazardous waste and mixtures of compounds. Enzymes can provide a ...
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AI tool helps match enzymes to substrates
A new artificial intelligence-powered tool can help researchers determine how well an enzyme fits with a desired target, helping them find the best enzyme and substrate combination for applications ...
Enzymes are the molecule factories in biological cells. However, which basic molecular building blocks they use to assemble target molecules is often unknown and difficult to measure. An international ...
It is well known in physics and chemistry that equal charges repel each other, while opposite charges attract. It was long assumed that this principle also applies when enzymes – the biological ...
Enzymes are essential for life and are one of the most important types of protein in the human body. Studying enzyme kinetics provides information about the diverse range of reactions in the human ...
Measuring Enzyme Kinetic Parameters with the ITC Universal Enzyme Assay Method Enzymes are important in drug discovery and development since they constitute approximately one-half of all known drug ...
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