MPN-BP transformation is driven by sequential mutations disrupting genomic stability, with TP53 mutations being strong predictors of progression. TP53 mutations confer a selective growth advantage, ...

In Lake Malawi, hundreds of species of cichlid fish have evolved with astonishing speed, offering scientists a rare opportunity to study how biodiversity arises.

A research team has elucidated the role of polyploidy in the evolution and breeding of vegetable crops, leveraging advanced sequencing technologies to dissect the genetic and epigenetic nuances of ...

Alex Nguyen Ba receives funding from the Natural Sciences and Engineering Research Council of Canada. University of Toronto provides funding as a founding partner of The Conversation CA. University of ...

Evolution is perhaps the most extraordinary story ever told—a tale spanning billions of years that connects every living thing on Earth through an intricate ...

In most developing tissues, signals called morphogens act like lighthouses, guiding nearby cells toward their fate and telling them what to become. Each cell relies on such signals for organized ...

Our team is led by Dr. Caroline Colijn and includes researchers who are applying mathematical and statistical tools to answer important questions in the areas of genomics, epidemiology, biology and ...