Light-sheet microscopy has emerged as a transformative imaging modality that enables rapid, three‐dimensional visualisation of biological specimens with minimal photodamage. By illuminating samples ...

Light microscopy is a cornerstone in life sciences technology, having experienced considerable diversification since its inception. This development becomes visible when considering the distinctive ...

descSPIM enables three-dimensional imaging of diverse tissues like neural cells and cancerous tumors. The widespread dissemination and adoption of descSPIM can accelerate biomedical discoveries. Three ...

(A) When a traditional Gaussian beam is used, diffraction causes the illumination beam to widen at the edges. (B) Joint optimization scheme. A network predicts the positions of beads in the focal ...

The lightsheet system is perfect for capturing 3D fluorescent images of organisms, tissue explants, and cell cultures over long periods. Basically, it shines a thin sheet of laser light on a slice of ...

Researchers at Istituto Italiano di Tecnologia (IIT-Italian Institute of Technology) have developed an innovative microscopy ...

Analyzing the response of cells to heat shock is an established way to study the behavior of cells in changing conditions, and understand their natural survival mechanisms. A project at the University ...

Confocal microscopy is a specialized fluorescence imaging technique that scientists use to acquire images at greater resolution than conventional microscopy. 1 In addition to scanning the lateral x ...

Advances in low-light imaging are attractive for bioimaging applications, as they should reduce the risks of sample damage and phototoxicity. The difficulty so far has been to maintain an image ...

As the second leading cause of death globally, cancer is a worldwide health crisis, particularly as life expectancies continue to increase. In its final stages, cancer spreads throughout the body in a ...