Allergic diseases represent a major global health burden, placing significant strain on health care systems worldwide. Severe ...

For many patients with diverse and seemingly unrelated symptoms, obtaining an accurate diagnosis can take years of specialist visits and inconclusive tests. Mast cell activation syndrome, a disorder ...

Mast cells are pivotal effectors in immune responses, acting as both sentinels and mediators in allergic and inflammatory processes. Their ability to rapidly degranulate and release a myriad of ...

According to an international multicenter study, CD2-negative mast cells are associated with significantly reduced overall survival in patients with SM. Patients with CD2-negative mast cells have ...

Blueprint Medicines’ focus on Ayvakit continues to pay off, which has ample untapped revenue potential in advanced and indolent systemic mastocytosis. Additionally, their pipeline includes other ...

Editor’s note: Dr. Lee Pickett has retired, but Creators continues to distribute columns from her archive. This one is from 2022. Q: My Lab mix has a mast cell tumor. What can you tell me about this ...

In dogs, mast cell tumors are the most common malignant skin tumors, accounting for approximately 16–21% of all skin cancers. These tumors can appear anywhere on the body but are most frequently found ...