A team of scientists has uncovered a critical mechanism that could pave the way for safer and more effective obesity ...

“The topline results from Ascletis’ Phase 3 open-label acne trial in China build additional confidence in the clinical potential of FASN inhibition in acne,” said David Happel, Chief Executive Officer ...

A protein long implicated in diabetes and obesity may hold the key to treating Alzheimer’s disease by reinvigorating the brain’s immune system. New research suggests that blocking this protein, known ...

The Guggenheim and Oppenheimer fireside chats will be available in the Investors & Media section of Sagimet’s website at www.sagimet.com, with an archived replay available for 90 days following the ...

Metabolic reprogramming in fibrotic lung diseases involves key metabolites like lactate, succinate, and 2-hydroxyglutarate, driving inflammation and fibroblast activation. Lactate accumulation ...

A research team, led by Professor Alan Wong Siu-lun (third left), Professor Leung Suet-yi (third right) and Professor Helen Yan Hoi-ning (second left), has revealed that nerves in the digestive system ...

This article summarizes metabolic reprogramming in prostate cancer (PCa). Early PCa relies more on glycolysis. castration-resistant prostate cancer (CRPC) enhances glucose metabolism, shifts ...

Prostate cancer (PCa) is one of the most common malignant tumors among men worldwide. Following androgen deprivation therapy (ADT), the disease often progresses to castration-resistant prostate cancer ...

MD Anderson studies reveal how cancer cells rewire metabolism to spread. A glucose–fructose mix promotes colorectal metastasis via cholesterol pathways, while fatty-acid oxidation driven by ACBP ...