Breast cancer remains the most prevalent malignancy among women worldwide, posing a critical challenge to global health. Amid the complexities of this disease, an emerging focus on metabolic ...

Breast cancer development is not solely the result of cancer cells acting independently, it involves a dynamic and complex ecosystem composed of cancer cells, immune cells, fibroblasts, adipocytes, ...

Senescence, aging, and age-related diseases represent complex biological phenomena with significant impacts on human health, and metabolism and metabolomics play pivotal roles in understanding their ...

Metabolic diseases, including but not limited to diabetes mellitus, metabolic-associated fatty liver disease, hyperlipidemia, hyperuricemia, and gout, are ...

In the battle against type 1 diabetes (T1D), one researcher at the Medical University of South Carolina (MUSC) is leading a ...

Dysregulation of lipid metabolism promotes EMT (by Figdraw). Down-regulation of ELOVL2 promotes EMT in breast cancer by up-regulating expression of SREBP1/2. TIME associated with lipids in breast ...

Alzheimer’s may advance by breaking the brain’s internal clock—and resetting it could help fight the disease. Alzheimer’s disease often interferes with a person’s normal daily patterns. Early warning ...

In 1980, Ludwig and colleagues described the histologic features of a newly identified chronic liver condition referred to as nonalcoholic steatohepatitis (NASH) and noted that the majority of the ...