Inflammation is the sign that our body is defending itself against an aggression. But when this response escalates, for example in the brain, it can lead to serious neurological or psychiatric ...

Microglia, the primary immune cells in the brain, play vital roles in neurogenesis, homeostasis maintenance, synaptic plasticity, and brain development. They are widely used in monoculture for ...

Microglia are the brain's immune cells that clean out debris, such as damaged proteins and old cell parts, to keep the organ healthy. But the very properties that make these cells so useful might also ...

Microglia respond to proteinopathies by changing their shapes and expression profiles in different ways. Here’s one that has been somewhat overlooked: rod-shaped microglia. These long, straight cells ...

As resident trash collectors, microglia survey the brain in search of detritus for disposal. How do they recognize the debris? In the case of plaques, a cell-surface receptor might be involved, though ...

Inflammation is the sign that our body is defending itself against an aggression. But when this response escalates, for example in the brain, it can lead to serious neurological or psychiatric ...

Scientists have found that blocking microglia (specialist immune cells in the brain) prevents infant forgetting ("infantile amnesia") and improves memory in mice, suggesting that microglia may ...

Blocking microglia prevents infant forgetting and improves memory in mice, suggesting that these specialist immune cells in the brain may actively manage memory formation and dictate what, and when, ...

These cells act like cleaners. They remove waste, broken proteins, and old cell parts so that the brain can continue working properly. However, new research suggests that this helpful cleaning process ...