Electron micrographs show typical microglia in the prefrontal cortex of a 92-year-old healthy female (left) and dark microglia a 91-year-old female patient with Alzheimer’s disease (right). Microglia, ...
Targeting nuclear pore complex and therapeutic response in glioblastoma stem cells. This is an ASCO Meeting Abstract from the 2022 ASCO Annual Meeting I. This abstract does not include a full text ...
For years, researchers considered Alzheimer’s disease (AD) an amyloid beta and neuron-related condition. But having trained as a pathologist, Thomas Montine, who is now a neuropathology researcher at ...
Numerous studies have cast TREM2-expressing microglia as good guys in the Alzheimer’s brain, but new research suggests some play a darker role. In the April 18 Nature Neuroscience, researchers led by ...
In this interview, Dr. Tilman explains the functions of iPSC-derived microglia and their relevance to conditions like Alzheimer’s and other neurodegenerative diseases. Microglia are the primary immune ...
Tiny immune cells called microglia protect the central nervous system (CNS) in a multitude of ways: They provide innate immunity, shape neurodevelopment, maintain homeostasis and modulate neurological ...
Lead author Neta Rosenzweig, PhD, of the Ann Romney Center for Neurological Diseases, and senior author Oleg Butovsky, PhD, of the Ann Romney Center and Gene Lay Institute of Immunology and ...
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