Persistent inflammation may influence neurodegeneration through microglial activation, yet evidence remains hypothesis driven ...
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Alzheimer’s plaques decline after CAR-T immune cell treatment in preclinical study
By Hugo Francisco de Souza A novel CAR-T cell approach targets amyloid plaques in preclinical Alzheimer models, raising the ...
Microglial activation is a determining factor that allows amyloid-beta accumulation to drive reactive astrogliosis, amplifying inflammatory responses in the brain. This was the conclusion of a study ...
Researchers at University of Tsukuba have discovered that an immunosuppressive drug affects microglia, the resident immune ...
A study by researchers from Fujita University reveals that hypernatremia enhances NFAT5 and NO production in microglia and minocycline mitigates this response. The image above is a schematic showing ...
The idea that infiltrating T cells contribute to a neurodegenerative environment in aging and in Alzheimer’s disease has gotten another boost. In the June 27 Nature Neuroscience, scientists led by ...
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