Cyclic GMP pathway is critical for inducing long–term sensitization of nociceptive sensory neurons
In various species, peripheral injury produces long–lasting sensitization of central and peripheral neurons representing the affected area 1,2. In Aplysia, memory–like traces (lasting days or weeks) ...
Liver disease sometimes causes hepatic encephalopathy, which involves brain damage, personality changes, and intellectual impairment due to hyperammonemia (high levels of ammonia in the blood).
We recently demonstrated early metabolic alterations in the dystrophin-deficient mdx heart that precede overt cardiomyopathy and may represent an early "subclinical" signature of a defective nitric ...
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