Immunological memory - the ability to respond to a previously encountered antigen, or foreign substance, with greater speed and intensity on re-exposure is a hallmark of adaptive immunity. Innate ...
Yunseon Yang, Jae-Jin Song, Yu Ree Choi, Seong-hoon Kim, Min-Jong Seoka, Noviana Wulansari, Wahyu Handoko Wibowo Darsono, Oh-Chan Kwon, Mi-Yoon Chang, Sang Myun Park, Sang-Hun Lee Proceedings of the ...
The potential effects of astrocyte dysfunction in neurodegenerative diseases are summarized in Figure 2. AD is characterized clinically by cognitive loss in two or more domains, including memory, ...
The Alzheimer's disease pathological cascade unfolds in the brain over decades, amidst a menagerie of cell types reacting to change. How, and when, does each cell type contribute to the process? A ...
New experiments reveal how astrocytes tune neuronal activity to modulate our mental and emotional states. The results suggest ...
Inhibition of autophagy, specifically in astrocytes, prevents the removal of Aβ via autophagic vesicles, which could worsen dementia pathology. Disclaimer: AAAS and EurekAlert! are not responsible for ...
Move over, amyloid, reactive astrocytes and activated microglia may be the main drivers of the Alzheimer’s disease pathological cascade. In the November 6 Nature Neuroscience, scientists led by Pedro ...
Parkinson's disease (PD) is a neurodegenerative disorder in which the α-synuclein protein abnormally aggregates within brain cells, causing neuronal damage. Through international collaboration, ...