CluMPS—Clusters Magnified by Phase Separation—is a fluorescent reporter strategy for detecting protein clusters. It promises to facilitate the visualization of protein clusters that are too small to ...

A multi-institutional research collaboration has revealed that the microtubule network (*1), which plays a vital role in cell construction and polarization (*2), utilizes the phase separation (*3) ...

An increasing understanding of how materials crystallize has transformed modern science and technology, from display technologies such as LCDs to solar panels and the analysis of biological samples to ...

Scientists elucidated characteristics of PAS through observing the Atg protein using a fluorescence microscope and successfully reconstituted PAS in vitro. The team revealed, for the first time, that ...

Liquid-liquid phase separation is not a precursor to formation of amyloid fibrils, a pathological hallmark of Parkinson's disease, shows study. Rather, the formation of protein into liquid droplets ...

A pioneering optical technique developed by the Prevedel Group at EMBL (the European Molecular Biology Laboratory, based in Heidelberg, Germany) allows neuroscientists to observe live neurons deep ...

One variation of electron microscopy is transmission electron microscopy (TEM). In a TEM experiment, the electron beam passes through the sample and the electrons are directly imaged onto an electron ...

New device could be used to observe structures as small as individual proteins, as well as the environment in which they move ...