Sodium channels are implicated in many serious conditions such as heart disease, epilepsy and pain, making them an important potential target for drug therapies. Unfortunately, there is still much ...

Scientists have determined the atomic structure of a sodium channel, a pore in membranes of excitable cells, such as brain or heart cells, that emit electrical signals. They gate charged particles ...

The voltage-gated sodium channel is essential for nerve cells to function. But how does it work? A low-resolution, three-dimensional structure provides some provocative insights. Sensation, emotions, ...