NLRP3 is a validated anti-inflammatory target that mediates the release of proinflammatory cytokines IL-1β and IL-18, and ISM5059 targets systemic inflammatory conditions by targeting NLRP3 and ...
WASHINGTON, DC—Incidental coronary artery calcium (CAC) is often seen on chest CTs in patients with immune-mediated inflammatory diseases who don’t have atherosclerotic cardiovascular disease (ASCVD), ...
Cytokines are regulatory proteins involved in cell proliferation, differentiation, inflammation, and hematopoiesis. An excessive immune response triggered by external viruses can lead to a severe ...
A new study exploring the investigational therapy, Zorpo-cel, met its primary safety and secondary efficacy endpoints in ...
Eight children with severe autoimmune diseases who did not respond to conventional therapies were able to completely stop ...
Familial HLH is a success story in modern medicine. Initially a disease that was largely unknown and fatal, it is now understood on a molecular level and is curable. Moreover, HLH is an archetype of ...
The term scleritis describes a chronic inflammation that involves the outermost coat and skeleton of the eye. Disease can be isolated to the eye, but in up to half of affected individuals it occurs in ...
We report a rare case of acute neurological Behçet’s disease (neuro-BD) diagnosed concurrently with systemic Behçet’s disease ...
The ‘TL1A’ messenger protein of the immune system triggers gut-to-bone marrow reaction, increasing the colorectal cancer risk ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results