TLSs are highly organized structures that typically appear as clusters of B-cells containing FDCs. These clusters are then surrounded by T-cells and HEVs as shown schematically in Figure 1. We ...
- A collaborative study demonstrates that AI analysis of Tertiary Lymphoid Structures (TLS) in tumors can predict treatment response in non-small cell lung cancer patients SEOUL, South Korea, Aug. 21, ...
In this interview, we spoke with Associate Professor Diana Mechtcheriakova about how lymphoid structures and germinal centers are unlocking new prognostic insights into colorectal cancer, and with ...
A newly described stage of a lymph node-like structure seen in liver tumors after presurgical immunotherapy may be vital to successfully treating patients with hepatocellular carcinoma, according to a ...
REZILIENT3: Phase 3 study of zipalertinib plus chemotherapy in patients with previously untreated, advanced nonsquamous non-small cell lung cancer (NSCLC) harboring epidermal growth factor receptor ...
Findings from a new study, led by researchers at Dartmouth's Geisel School of Medicine and published in Nature Immunology, have uncovered key functional differences in macrophages—a type of white ...
CAMBRIDGE, United Kingdom, March 05, 2024 (GLOBE NEWSWIRE) -- Mestag Therapeutics (“Mestag”), a biotech company harnessing new insights into fibroblast-immune interactions to develop impactful ...
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Targeting tertiary lymphoid structures for cancer treatment
A research team at Memorial Sloan Kettering Cancer Center (MSK) has made new insights into how the body forms immune cell ...
Association between PD-1 expression on tumor-infiltrating regulatory T cells and resistance to first-line nivolumab in advanced clear cell renal cell carcinoma: Insights from the HCRN GU16-260 ...
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