DNA's iconic double helix does more than "just" store genetic information. Under certain conditions, it can temporarily fold ...
DNA's iconic double helix does more than "just" store genetic information. Under certain conditions it can temporarily fold into unusual shapes.
Abstract: Cyclic peptides become attractive therapeutic candidates due to their diverse biological activities. However, existing deep learning-based sequence design models, such as ProteinMPNN, are ...
A new USC Leonard Davis School-led study highlights how transposons—commonly called "jumping genes" because of their ability to move to different parts of the genome—are associated with age-related ...
A graphic representation of a round, lumpy, blue protein and a single, comblike, purple strand of RNA interacting with a twisted, double, blue strand of DNA that separates where it meets the RNA. A ...
minecraft 1.20.1 froge 47.4.10 and MSS 5.0.21 the diorite house structure cannot load due to the following error: [20:58:22] [Server thread/ERROR]:Couldn't load structure mss:diorite_house ...
First of all, thank you for open-sourcing boltzgen. I have successfully reproduced several design tasks using the CLI pipeline (design → inverse_folding → folding → analysis). I want to supply one or ...
Abstract: Recently, a range of effective methods have been developed for predicting protein-protein interactions (PPIs). Among them, the methods based on data derived from protein sequences and ...
In recent years, the integration of computational and machine learning techniques has dramatically advanced our understanding of protein function and engineering. As proteins underpin virtually every ...
The identification and visualization of functional elements within biological sequences offers visual presentation for biologists to integrate annotation, and also helps them to produce high-quality ...
This valuable work presents an interpretable protein-DNA Energy Associative (IDEA) model for predicting binding sites and affinities of DNA-binding proteins. While the method is convincing, it ...