The direct pathway, sometimes known as the direct pathway of movement, is a neural pathway within the central nervous system (CNS) through the basal ganglia which facilitates the initiation and …

Oct 30, 2023 · Three major pathways emerge from the basal ganglia, which project onto various structures of the brain, communicating with them. They are called the direct (excitatory), indirect …

The key to understand what determines the activity of both direct and indirect pathways are in the nigrostriatal dopaminergic pathway. Dopamine acts throughout the striatum and simultaneously …

Nov 6, 2025 · Explore, cut, dissect, annotate and manipulate our 3D models to visualise anatomy in a dynamic, interactive way. The anatomy of the basal ganglia is complex since it is spread throughout …

For motor control, there are two main circuits: the direct pathway and the indirect pathway. These circuits have opposing actions when activated by cortical neurons.

The primary purpose of the direct pathway is to facilitate initiation of voluntary movements. This is accomplished by a process of disinhibition, which modulates the activity of the motor cortex by …

Jun 26, 2025 · To initiate a voluntary movement, the brain uses the direct pathway. This route functions as a “go” signal, releasing the brakes on a desired motor action. The process begins when the …

In the direct pathway, the cerebral cortex sends excitatory projections to the striatum. Then, the striatum sends inhibitory projections to the internal globus pallidus.

Jul 17, 2023 · What is the direct pathway (striatonigral pathway) and how does it work? 🤔🧠 Find out everything you need to know in this handy guide to the direct pathway of the basal ganglia.

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